QUANTITATIVE PROTEOMICS REVEALED THE PHARMACODYNAMIC NETWORK OF BUGU SHENGSUI DECOCTION PROMOTING OSTEOBLAST PROLIFERATION

Quantitative Proteomics Revealed the Pharmacodynamic Network of Bugu Shengsui Decoction Promoting Osteoblast Proliferation

Background and ObjectiveWith high morbidity and disability, osteoporosis is a worldwide bone metabolism disease, regulated by complex pathological processes.Insufficient osteogenesis is greatly essential to osteoporosis.Traditional Chinese Medicine, a complex natural herbal medicine system, has increasingly attracted attention all over the world.Bu

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Feasibility of a tapering opioids prescription program for trauma patients at high risk of chronic consumption (TOPP-trauma): protocol for a pilot randomized controlled trial

Abstract Background Opioid use disorder (OUD) and deaths related to the chronic use of opioids have increased significantly over the last two decades.Chronic consumption of opioids has been documented in many patients with traumatic injuries.Preliminary research findings have shown that interventions using cognitive-behavioral strategies were a pro

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